Trieste is the capital city of the Friuli Venezia Giulia region in northeast Italy. A port city, it occupies a thin strip of land between the Adriatic coast and Slovenia’s border on the limestone-dominated Karst Plateau. Italian, Austro-Hungarian and Slovenian influences are all evident in its layout, which encompasses a medieval old city and a neoclassical Austrian quarter.

In Croatia, the Old Town of Split wraps around the luxurious palace where the Roman emperor Diocletian lived out his last days after abdicating in AD 305. Today, this remarkable white limestone palace, a UNESCO Site, awaits your discovery. Part luxurious villa, part military camp, the palace is enclosed by imposing walls and connected by roads linking the eastern Silver Gate with the Iron Gate to the west. Within: an octagonal domed mausoleum, temples and a monumental court accessing the imperial apartments.

Your harbor on this island was created by a volcano in 1500 BC., and the effect is still explosive: steep cliffs rise from sea level, cubist white houses glow in the Aegean sun. Sample shore excursion: Panoramic Santor ni.

Informality rules on this sunny isle where pleasure-seekers from around the world come to play. Ramble along narrow streets past white-washed houses and blue-domed churches, bouganvillea-covered walls and thread-like, step-laden footpaths leading everywhere.

Kusadasi in Turkey is the gateway to one of the most legendary cities of the ancient world: Ephesus. St. Paul preached in its Great Theater, while the facade of the Celsus Library survives as a testament to the city’s role as a center of learning and culture. Not far from Ephesus, the Temple of Artemis (also known as the Temple of Diana), one of the Seven Wonders of the ancient world, once stood, drawing pilgrims from around the Mediterranean. While it no longer stands, it is possible to walk amongst its foundations and the remains of its towering columns. Other historic sites can also be found nearby: The House of Mary is believed to be the home of Jesus’s mother at the end of her life, and the Basilica of St. John, constructed in the 6th century, marks the location of his tomb. (Like Mary, he spent his final years in Ephesus.) Nearby, the Selcuk fortress reflects the period of Byzantine and Ottoman control of the region. From ancient wonders to holy sites, there are few ports in the Mediterranean as magical as Kusadasi, and a day here is a day spent in the company of some of antiquity‘s greatest figures.

Blurring the line between east and west, Istanbul stands at the crossroads of two continents. The city‘s architecture is rivalled only by its spectacular natural setting on the Bosphorus Strait. See the Blue Mosque, the Topkapi Palace and the Byzantine Church of St Sophia. Take time to wander through the Grand Bazaar or the Spice Market and sample baklava and shish kebabs.

Blurring the line between east and west, Istanbul stands at the crossroads of two continents. The city‘s architecture is rivalled only by its spectacular natural setting on the Bosphorus Strait. See the Blue Mosque, the Topkapi Palace and the Byzantine Church of St Sophia. Take time to wander through the Grand Bazaar or the Spice Market and sample baklava and shish kebabs.

No modern metropolis is more steeped in myth than Athens, Greece. From the gritty port of Piraeus—gateway to Greece’s fabled isles—to the Parthenon—eternal symbol of Western civilization—Athens has attracted adventurers and classicists for centuries. This heritage is still very much alive for modern visitors sightseeing in Athens: ancient stadiums and temples dwell alongside apartment blocks, modern performances are staged in the marble amphitheaters where Greek drama was born and millennia-old monuments are scattered in the archaeological park that circles the Acropolis. One of the world’s oldest maritime powers, Athens is blessed with a balmy climate and stunning coastline. The seaside suburbs of Athens are scalloped with sandy beaches, fancy yacht clubs and glamorous beach bars. While the Athenian lifestyle is known for late-night dinners and dancing until dawn, the city shines brightly by day in the bustling markets, lively cafés and fascinating museums that illuminate Greece‘s past and present. Contemplate the magnitude of all that culture and ancient tourist attractions while marveling at the sun setting into the Aegean or rising over the Acropolis.